Frontiers in Neuroscience 2025 Evidence: Works

Omega-3 Fatty Acids Improve HRV in Meta-Analysis

Summary

Meta-analysis of randomized controlled trials found that omega-3 fatty acid supplementation (EPA and DHA) consistently improves HRV metrics, with effects appearing after 8-12 weeks of supplementation.

Methods

Meta-analysis of 15 RCTs with HRV outcomes

Key Findings

  • 1-2g daily EPA/DHA showed most consistent benefits
  • RMSSD improved by 5-15% on average
  • Benefits more pronounced in those with lower baseline omega-3 status
  • Effects take 8-12 weeks to fully manifest

Limitations

Heterogeneous study designs, varying doses and formulations

What This Means for You

Omega-3 supplementation (fish oil or algae-based) at 1-2g of EPA+DHA daily has the strongest nutritional evidence for HRV improvement. Give it 2-3 months to see effects.

Source

Read the original paper in Frontiers in Neuroscience ↗

Added to HRV Zone: 2025-01-07

Related Topics

Explore More