PMC 2025 NEW Evidence: Works

Chronic Low Back Pain Associated with Reduced Parasympathetic Activity

Summary

Adults with chronic low back pain show reduced parasympathetic activity compared to pain-free controls, supporting the link between chronic pain and autonomic dysfunction.

Methods

HRV comparison between adults with chronic low back pain and healthy controls

Key Findings

  • Decreased vagal activity in chronic low back pain patients
  • Reduced parasympathetic modulation of pain responses
  • Autonomic regulation involved in pain modulation
  • Findings consistent with other chronic pain conditions

Limitations

Cross-sectional design, cannot determine causality

What This Means for You

Chronic pain and low HRV often go together. Interventions that boost parasympathetic activity—like slow breathing, meditation, and gentle exercise—may help both your HRV and your pain levels.

Source

Read the original paper in PMC ↗

Added to HRV Zone: 2026-01-23

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