Frontiers in Neurology 2025 NEW Evidence: Works

Sleep Deprivation Significantly Reduces HRV (Meta-Analysis)

Summary

Meta-analysis of 11 randomized controlled trials confirms that sleep deprivation causes significant decreases in parasympathetic HRV markers and increases in sympathetic activation.

Methods

Systematic review and meta-analysis of 11 RCTs with 549 participants

Key Findings

  • RMSSD significantly decreased after sleep deprivation (p < 0.05)
  • LF power significantly increased (sympathetic activation)
  • LF/HF ratio significantly increased after sleep loss
  • Effects consistent across different sleep deprivation protocols

Limitations

Heterogeneous study designs, mostly acute sleep deprivation

What This Means for You

Even one night of poor sleep measurably shifts your nervous system toward sympathetic dominance. This explains why your HRV drops after bad sleep and why sleep is the foundation of HRV optimization.

Source

Read the original paper in Frontiers in Neurology ↗

Added to HRV Zone: 2026-01-21

Related Topics

Explore Further

Practical guides related to this research

Explore More