Drug and Alcohol Dependence 2020 Evidence: Doesn't Work

Opioid Withdrawal Causes Large Drops in HRV

Summary

Opioid withdrawal is characterized by significant autonomic dysfunction, with large reductions in parasympathetic HRV and sympathetic hyperactivity. HRV metrics may help predict withdrawal severity and treatment response.

Methods

HRV monitoring during naloxone-induced opioid withdrawal

Key Findings

  • HF-HRV and RMSSD significantly lower during withdrawal
  • Heart rate and blood pressure increase substantially
  • Sympathetic hyperactivity drives withdrawal symptoms
  • HRV changes predict treatment outcomes
  • Medications targeting ANS may help withdrawal

Limitations

Acute withdrawal setting, various opioid types

What This Means for You

During opioid recovery, expect autonomic instability. HRV monitoring can track your physiological recovery alongside psychological progress. Interventions targeting parasympathetic function may help.

Source

Read the original paper in Drug and Alcohol Dependence ↗

Added to HRV Zone: 2025-01-10

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